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Heroin Addiction and Related Clinical Problems: 2017, 19, N3 (pages: 49 - 56)

Neuropsychological Deficits in Young Drug-Addicts

Parolin M., Simonelli A., Cristofalo P., Mapelli D., Bacciardi S., Maremmani A.G.I., Cimino S., Babore A., and Cerniglia L.

Summary: Background: Adolescence is a highly vulnerable age for experimenting with drugs; increasing evidence attests that several substances might have detrimental effects on cognitive functioning in this developmental phase, when prefrontal brain areas are still immature and may actually be the main target of the neurotoxic effects of drugs. There are still, in any case, too few studies that specifically address early adulthood. Aim: The present study aims to investigate neuropsychological performance in young drug addicts in residential treatment (aged 18-24). Methods: 41 young drug addicts, after admission to residential treatment, were compared with 27 subjects in the control group. A battery of neuropsychological tests (Brief Neuropsychological Exam-2) was administered to detect possible cognitive impairments. Descriptive and non-parametric statistics (Pearson's chi square test) were performed. Results and conclusions: Findings suggest that drug dependence in youth is distinguished by neuropsychological deficits, in particular, attention and executive function impairments – issues that now call for tailored and innovative treatment approaches.