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Heroin Addiction and Related Clinical Problems: 2013, 15, 1 (pages: 39 - 44)

Changes in Sleep Quality and Alertness in Opiate-Dependent Subjects after 23 months stable Methadone and Buprenorphine Maintenance Treatment. A pilot exploratory report

Sarram S., Debrabant R., Fatseas M., Daulouède J.-P., Sagaspe P., Aillard J.T., Philip P., Auriacombe M.

Summary: We evaluated changes in subjective sleep quality in 40 opiate-dependent patients in stable methadone and buprenorphine maintenance treatment. Scores that measured sleep were compared with available normative data. An overall improvement in sleep problems has been reported since the onset of treatment 23 months (SD 19) ago. Two-thirds of the subjects reported an increase in their quality of sleep and daytime alertness as compared with the period before treatment. Compared with normative data, however, quality of sleep remained highly impaired in all participants with low sleep efficiency. Patients with comorbid depression and anxiety were the most impaired.