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Heroin Addiction and Related Clinical Problems: 2007, 09, 1 (pages: 45 - 54)

Paxil (Paroxetine) in Complex Therapy in Heroin Addicts

Rokhlina M., Kitkina T., Gubanov G.

Summary: The efficiency of Paroxetine was studied in 27 males with heroin addiction (average age: 26.2 years, average disease duration: 3.4 years) undergoing detoxification. After 3-4 days of paroxetine (initial dose 20 mg/day, maximum dose 40 mg/day) the first improvement of affective symptoms were noticed. By the 14th day of treatment, affective discomfort had been arrested in most cases. On the whole paroxetine can be considered an effective medicine for contrasting affective discomfort of heroin addicts in the post-withdrawal stage, as long as agonist compounds are not available.